Initiative to test drug combos guided by tumor biology

Initiative to test drug combos guided by tumor biology

Cell culture of human breast cancer conditionally reprogrammed cells. CREDIT: Ewa Krawczyk, National Cancer InstituteGeorgetown Lombardi Comprehensive Cancer Center, National Institutes of Health The National Cancer Institute (NCI), part of the National Institutes of...
Protein helps cancer-causing viruses evade immune response

Protein helps cancer-causing viruses evade immune response

Viruses (EBV and KSHV) surrounding cells. CREDIT: Damania Lab, UNC School of Medicine The viruses Kaposi sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV) have been linked to several cancers. For the first time, UNC School of Medicine scientists have...
Scientists develop vax to kill, prevent brain cancer

Scientists develop vax to kill, prevent brain cancer

Scientists developed a bifunctional therapeutic strategy by transforming living tumor cells into a therapeutic, using the gene editing tool CRISPR-Cas9 and repurposing them to release tumor cell killing agent. In addition, the engineered tumor cells were designed to...
UK patient gets novel treatment for T-cell leukemia

UK patient gets novel treatment for T-cell leukemia

In May 2022, Alyssa, 13 from Leicester, became the first reported patient in the world to receive base-edited T-cells at Great Ormond Street Hospital for Children (GOSH), in collaboration with the UCL Great Ormond Street Institute of Child Health (UCL GOS ICH), to...
Experimental cancer vaccine shows promise in mice

Experimental cancer vaccine shows promise in mice

An experimental therapeutic cancer vaccine induced two distinct and desirable immune system responses that led to significant tumor regression in mice, report investigators from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National...